著   者：(美）Dan L.Longo等                                           

字  数：1480千字

书   号：978-7-5596-1102-4                       

页  数：848           

出   版：北京联合出版公司    

              后浪出版公司                      

印  张：53

尺   寸：216毫米×276毫米                         

开  本：1/16

版   次：2018年1月第1版                        

装  帧：平装

印   次：2018年1月第1次印刷                    

定  价：495.00元

正文用纸：铜版纸

编辑推荐

•每一章都包含相关的遗传学、细胞生物学、病理生理学和特殊疾病诊疗的信息

•更新了血细胞生成、癌症细胞生物学和癌症预防等内容

•用临床诊断与治疗的思维方式解释病理生理

•高水平学术审核，使本书保持专业领先水平

•附录提供了有临床意义的实验室数据

著者简介

Dan L.Longo博士是《哈里森内科学》负责血液学和肿瘤学内容的编辑,几本著名的血液学和肿瘤学教科书的作者，同时也是《新英格兰医学杂志》的副主编,哈佛医学院的教授。Dan L.Longo博士是享誉中外的内科学专家之一。

内容简介

  全书57章,由75位著名专家共同完成，全书包括血液学基础、血液系统疾病的临床表现、贫血、骨髓增殖性疾病、凝血障碍、癌症生物学等内容，是以血液学与肿瘤学为主题的前沿、全面的专业书。本书以简洁、全彩为特色，提供本领域最新的具有科学严谨性和权威性的知识，非常适合教师、诊所和病房医生使用，也是医学生认证考试的必备书。

目  录

Contributors. viii

Preface. xi

SECTION I

THE CELLULAR BASIS OF HEMATOPOIESIS

1 Hematopoietic Stem Cells. . 2

David T. Scadden, Dan L. Longo

SECTION II

CARDINAL MANIFESTATIONS OF

HEMATOLOGIC DISEASE

2 Anemia and Polycythemia. . .. 10

John W. Adamson, Dan L. Longo

3 Bleeding and Thrombosis. . 22

Barbara A. Konkle

4 Enlargement of Lymph Nodes and Spleen. . 32

Patrick H. Henry, Dan L. Longo

5 Disorders of Granulocytes and Monocytes. . 41

Steven M. Holland, John I. Gallin

6 Atlas of Hematology and Analysis

of Peripheral Blood Smears. . .. 57

Dan L. Longo

SECTION III

ANEMIAS

7 Iron Deficiency and Other

Hypoproliferative Anemias. . .. 72

John W. Adamson

8 Disorders of Hemoglobin. . 82

Edward J. Benz, Jr.

9 Megaloblastic Anemias. . 96

A. Victor Hoffbrand

10 Hemolytic Anemias and Anemia

Due to Acute Blood Loss. . 111

Lucio Luzzatto

11 Bone Marrow Failure Syndromes Including

Aplastic Anemia and Myelodysplasia. . 131

Neal S. Young

12 Transfusion Biology and Therapy. . 146

Jeffery S. Dzieczkowski, Kenneth C. Anderson

SECTION IV

MYELOPROLIFERATIVE DISORDERS

13 Polycythemia Vera and Other

Myeloproliferative Neoplasms. . 158

Jerry L. Spivak

SECTION V

HEMATOLOGIC MALIGNANCIES

14 Acute Myeloid Leukemia. . .. 168

Guido Marcucci, Clara D. Bloomfield

15 Chronic Myeloid Leukemia. . .. 181

Hagop Kantarjian, Jorge Cortes

16 Malignancies of Lymphoid Cells. . 193

Dan L. Longo

17 Less Common Hematologic Malignancies. . 216

Ayalew Tefferi, Dan L. Longo

18 Plasma Cell Disorders. . 231

Nikhil C. Munshi, Dan L. Longo,

Kenneth C. Anderson

19 Amyloidosis. . .. 245

David C. Seldin, John L. Berk

SECTION VI

DISORDERS OF HEMOSTASIS

20 Disorders of Platelets and Vessel Wall. . .. 254

Barbara A. Konkle

21 Coagulation Disorders. . .. . 265

Valder R. Arruda, Katherine A. High

22 Arterial and Venous Thrombosis. . 278

Jane E. Freedman, Joseph Loscalzo

23 Deep Venous Thrombosis and

Pulmonary Thromboembolism. . . . . . . . . . . . . . . 285

Samuel Z. Goldhaber

24 Antiplatelet, Anticoagulant,

and Fibrinolytic Drugs. . .. 294

Jeffrey I. Weitz

SECTION VII

BIOLOGY OF CANCER

25 Cancer Genetics . . . . . . . . . . . . . . . . . . . . . . . . . . . .320

Pat J. Morin, Jeffrey M. Trent,

Francis S. Collins, Bert Vogelstein

26 Cancer Cell Biology . . . . . . . . . . . . . . . . . . . . . . . . .333

Jeffrey W. Clark, Dan L. Longo

SECTION VIII

PRINCIPLES OF CANCER PREVENTION

AND TREATMENT

27 Approach to the Patient with Cancer. . . . . . . . . . 360

Dan L. Longo

28 Prevention and Early Detection of Cancer. . . . . .373

Jennifer M. Croswell, Otis W. Brawley,

Barnett S. Kramer

29 Principles of Cancer Treatment. . . . . . . . . . . . . . .386

Edward A. Sausville, Dan L. Longo

30 Infections in Patients with Cancer. . . . . . . . . . . . . 422

Robert W. Finberg

31 Hematopoietic Cell Transplantation. . . . . . . . . . .436

Frederick R. Appelbaum

32 Neoplasia During Pregnancy . . . . . . . . . . . . . . . . .446

Michael F. Greene, Dan L. Longo

33 Palliative and End-of-Life Care. . . . . . . . . . . . . . . . 454

Ezekiel J. Emanuel

SECTION IX

NEOPLASTIC DISORDERS

34 Cancer of the Skin. . . . . . . . . . . . . . . . . . . . . . . . . . . 480

Walter J. Urba, Brendan D. Curti

35 Head and Neck Cancer . . . . . . . . . . . . . . . . . . . . . .494

Everett E. Vokes

36 Neoplasms of the Lung. . . . . . . . . . . . . . . . . . . . . . . 500

Leora Horn , Christine M. Lovly ,

David H. Johnson

37 Thymoma. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 526

Dan L. Longo

38 Breast Cancer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 529

Marc E. Lippman

39 Upper Gastrointestinal Tract Cancers. . . . . . . . . . 542

Robert J. Mayer

40 Lower Gastrointestinal Cancers. . . . . . . . . . . . . . .551

Robert J. Mayer

41 Tumors of the Liver and Biliary Tree. . . . . . . . . . . 561

Brian I. Carr

42 Pancreatic Cancer. . . . . . . . . . . . . . . . . . . . . . . . . . .576

Elizabeth Smyth, David Cunningham

43 Bladder and Renal Cell Carcinomas. . . . . . . . . . . .582

Howard I. Scher, Jonathan E. Rosenberg,

Robert J. Motzer

44 Benign and Malignant Diseases of the Prostate. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .589

Howard I. Scher, James A. Eastham

45 Testicular Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . .601

Robert J. Motzer, Darren R. Feldman,

George J. Bosl

46 Gynecologic Malignancies. . . . . . . . . . . . . . . . . . . . 607

Michael V. Seiden

47 Soft Tissue and Bone Sarcomas

and Bone Metastases. . . . . . . . . . . . . . . . . . . . . . . . . 616

Shreyaskumar R. Patel, Robert S. Benjamin

48 Primary and Metastatic Tumors

of the Nervous System. . . . . . . . . . . . . . . . . . . . . . .623

Lisa M. DeAngelis, Patrick Y. Wen

49 Carcinoma of Unknown Primary. . . . . . . . . . . . . .638

Gauri R. Varadhachary, James L. Abbruzzese

SECTION X

ENDOCRINE NEOPLASIA

50 Thyroid Cancer. . . . . . . . . . . . . . . . . . . . . . . . . . . . .646

J. Larry Jameson, Susan J. Mandel, Anthony P.

Weetman

51 Endocrine Tumors of the Gastrointestinal Tract

and Pancreas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .657

Robert T. Jensen

52 Multiple Endocrine Neoplasia . . . . . . . . . . . . . . . .685

Rajesh V. Thakker

53 Pheochromocytoma and

Adrenocortical Carcinoma. . . . . . . . . . . . . . . . . . .700

Hartmut P. H. Neumann

SECTION XI

REMOTE EFFECTS OF CANCER

54 Paraneoplastic Syndromes:

Endocrinologic/Hematologic. . 712

J. Larry Jameson, Dan L. Longo

55 Paraneoplastic Neurologic Syndromes

and Autoimmune Encephalitis. . .. 721

Josep Dalmau, Myrna R. Rosenfeld

SECTION XII

ONCOLOGIC EMERGENCIES AND LATE

EFFECTS AND COMPLICATIONS OF CANCER AND ITS TREATMENT

56 Oncologic Emergencies. . 732

Rasim Gucalp, Janice P. Dutcher

57 Late Consequences of Cancer

and Its Treatment. . 750

Carl E. Freter, Dan L. Longo

Review and Self-Assessment. . 757

Charles M. Wiener, Cynthia D. Brown,

Brian Houston

Index. 793

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