商品详情

产品信息
名称 菌菇免疫复合胶囊
规格 60粒(胶囊)
价格 $62.5(汇率7.2)
发货 广州保税仓(下单后24小时发货)
产品简介
Imm Defend是六种菌菇提取物的强大组合。这种特定的菌菇组合含有一系列被称为“生物反应调节剂(BRMs,Biological Response Modifiers)”的活性物质,以应对免疫挑战。

成分说明,非产品功效宣称!
菌菇富含多种各种多糖、萜类、甾醇和酚类化合物[1,2],这些化合物充当“生物反应调节剂(BRMs,Biological Response Modifiers)”,调节巨噬细胞、自然杀伤(NK)细胞和T淋巴细胞,有助于建立Th1/Th2的平衡。
香菇中的α-和β-葡聚糖是被广泛研究的生物活性化合物。在日本,从香菇中提取的α-葡聚糖通常用作膳食补充剂[3]。已发现α-葡聚糖可调节CD4和CD8 T细胞的功能[4]。补充香菇α-葡聚糖也导致NK细胞活性增加2.5倍[5]。对食用香菇的其他研究表明,C反应蛋白(CRP)降低,这是正常炎症平衡的标志,分泌型IgA(sIgA)增加[6]。
灵芝是使用历史悠久的菌类,在中药中有2000年的使用历史。对小鼠的研究发现灵芝提取物可以维持正常的炎症平衡[7]。灵芝多糖提取物补充剂也显示出免疫益处,NK细胞活性和Th1和Th2平衡特性增加[8,9]。五项随机对照试验的荟萃分析结果表明,服用灵芝补充剂的患者CD4和CD8细胞百分比增加[10]。在接受灵芝多糖补充剂12周的患者中,73.2%的患者观察到与细胞因子TNF-α和IL-1血浆浓度降低相关的生活质量改善[11]。
桦树茸是一种生长在桦树皮上的药用真菌。它含有白桦脂和白桦脂酸,这些化合物是有效的自由基清除剂,可以诱导受损细胞凋亡[12]。
冬虫夏草中的主要生物活性成分是虫草素,这是一种具有免疫调节特性的腺苷衍生物[13]。蛹虫草更容易大规模培养,其虫草素含量高于冬虫夏草[14]。
平菇是一种常见的食用蘑菇。平菇富含蛋白质,也是维生素B、维生素C、维生素D和几种矿物质的来源[15]。它们也是谷胱甘肽和真菌抗氧化剂麦角硫因的来源[16]。研究发现平菇中的一种新型泛素样蛋白可以抑制逆转录酶,这对免疫防御很重要[17]。
云芝富含PSK(多糖-K)和PSP(多糖肽)。作为一种生物反应调节剂,PSP已被发现可以积极调节免疫系统并增加T细胞增殖[18]。研究还表明,补充平蘑菇粉可以增加淋巴细胞计数和NK细胞活性[19]。
*旨在帮助了解产品所含成分的营养学研究,不代表产品的功效。产品不用于预防、诊断和治疗任何疾病。如患有任何疾病,请咨询专业人员。
推荐人群
推荐通过补充菌菇以应对免疫挑战的人群使用。
*UGN产品符合FDA和美国联邦贸易委员会关于营养补充剂产品相关疾病声明的监管要求,产品不用于预防、诊断和治疗任何疾病。如患有任何疾病,请咨询专业人员。
建议用量
参考文献
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[2]Daba A, Ezeronye O. Anti-cancer effect of polysaccharides isolated from higher basidiomycetes mushrooms. African Journal of Biotechnology. 2003;2(12):672-678.
[3]Shah SK, Walker PA, Moore-Olufemi SD, Sundaresan A, Kulkarni AD, Andrassy RJ. An evidence- based review of a Lentinula edodes mushroom extract as complementary therapy in the surgical oncology patient. JPEN J Parenter Enteral Nutr. Jul 2011;35(4):449-458.
[4]Ritz B. Active hexose correlated compound (AHCC) and immune outcomes in humans: A review. Natural Medicine Journal. 2011;3(1):3-7.
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[6]Dai X, Stanilka JM, Rowe CA, et al. Consuming Lentinula edodes (Shiitake) Mushrooms Daily Improves Human Immunity: A Randomized Dietary Intervention in Healthy Young Adults. Journal of the American College of Nutrition. 34 (6): 478-487. doi:10.1080/07315724.2014.950391.
[7]Stavinoha, W.B. Status of Ganoderma lucidum in the United States: Ganoderma lucidum as an anti-inflammatory agent. Proceedings of the 1st International Symposium on Ganoderma lucidum in Japan. Nov 17-18 1991. 99-103. Tokyo.
[8]Gao Y, Zhou S, Jiang W, Huang M, Dai X. Effects of ganopoly (a Ganoderma lucidum polysaccharide extract) on the immune functions in advanced-stage cancer patients.Immunol Invest. Aug 2003;32(3):201-215.
[9]Gao Y, Tang W, Dai X, et al. Effects of water-soluble Ganoderma lucidum polysaccharides on the immune functions of patients with advanced lung cancer. J Med Food. Summer2005;8(2):159-168.
[10]Jin X, Ruiz Beguerie J, Sze DM, Chan GC. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane Database Syst Rev. 2012;6:CD007731.
[11]Oka S, Tanaka S, Yoshida S, et al. A water-soluble extract from culture medium of Ganoderma lucidum mycelia suppresses the development of colorectal adenomas.Hiroshima J Med Sci. Mar 2010;59(1):1-6.
[12]Faass N. The healing powers of wild chaga; an interview with Cass Ingram, MD. Price-Pottenger Journal of Health and Healing. 2012;35(4):6-11.
[13]Zhou X, Luo L, Dressel W, et al. Cordycepin is an immunoregulatory active ingredient of Cordyceps sinensis.Am J Chin Med. 2008;36(5):967-980.
[14]Kim H.O., Yun J.W. A comparative study on the production of exopolysaccharides between two entomopathogenic fungi Cordyceps militaris and Cordyceps sinensis in submerged mycelial cultures. Journal of Applied Microbiology. 2005; 99(4):728-38.
[15]Wani B.A., Bodha R.H., Wani A.H. Nutritional and medicinal importance of mushrooms. Journal of Medicinal Plants Research Vol. 4(24), pp. 2598-2604.
[16]Kalaras MD, Richie JP, Calcagnotto A, Beelman RB. Mushrooms: A rich source of the antioxidants ergothioneine and glutathione. Food Chem. 2017 Oct 15;233:429-433. doi:10.1016/j.foodchem. 2017.04.109. Epub 2017 Apr 20. PMID: 28530594.
[17]Wang HX, Ng TB. Isolation of a novel ubiquitin-like protein from Pleurotus ostreatus mushroom with anti-human immunodeficiency virus, translation-inhibitory, and ribonuclease activities. Biochem Biophys Res Commun. 2000;276(2):587-593.
[18]Ng TB. A review of research on the protein-bound polysaccharide (polysaccharopeptide, PSP) from the mushroom Coriolus versicolor (Basidiomycetes: Polyporaceae). Gen Pharmacol. 1998;30(1):1-4. doi:10.1016/s0306-3623(97)00076-1
[19Torkelson CJ, Sweet E et al. Phase 1 clinical trial of Trametes versicolor in women with breast cancer. ISRN Oncol. 2012:10.5402/2012/251632.


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