自组装超分子结构：易溶液晶 Self-Assembled Supramolecular Architectures: Lyotropic Liquid Crystals

基本信息

Edited by:Nissim Garti, Ponisseril Somasundaran, Raffaele Mezzenga

Series:Wiley Series on Surface and Interfacial Chemistry

Format:Hardback 392 pages

Publisher:John Wiley & Sons Inc

Imprint:John Wiley & Sons Inc

ISBN:9780470281758

Published:6 Nov 2012

Weight:685g

Dimensions:240 x 165 (mm)

信息仅供参考，具体请以实物为准

书籍简介

本书将介绍自组装超分子结构领域的基础知识和新发展，以及它们与理解膜作为活性成分递送系统的功能的相关性。由于层次结构决定了它们的性能，因此将关注与溶致液晶构造相关的理论和设计方面：中间相，例如层状、六边形、立方体、海绵相胶束体。本书将向读者介绍机械方面、成分考虑、相内转变、溶解能力、药物包封和释放机制以及跨膜、透皮和其他传输现象。它将强调这些介观结构对药物、脂肪和保健食品的结晶和多晶型的重要性，并将讨论在界面和中间相通道内发生的有机和酶反应的区域选择性。本书将介绍这些中间相作为结晶或颗粒化介质在纳米颗粒和纳米晶体形成中的应用研究。各章将讨论其在医药、食品、化妆品、塑料、纸张、农业化学和工业应用领域的应用。

This book will describe fundamentals and recent developments in the area of Self-Assembled Supramolecular Architecture and their relevance to the understanding of the functionality of membranes as delivery systems for active ingredients. As the heirarchial architectures determine their performance capabilities, attention will be paid to theoretical and design aspects related to the construction of lyotropic liquid crystals: mesophases such as lamellar, hexagonal, cubic, sponge phase micellosomes. The book will bring to the reader mechanistic aspects, compositional considerations, transition within phases, solubilization capacities, drug entrapment and release mechanisms and transmembrane, transdermal, and other transport phenomena. It will stress the importance of these mesostructures to crystallization and polymorphism of drugs, fats, and nutraceuticals and will discuss regioselectivity of organic and enzymatic reactions that take place at interfaces and within the channels of the mesophase. The book will bring studies on the use of these mesophase as crystallization or particulation media for the formation of nanoparticles and nanocrystals. Chapters will discuss applications in the areas of pharmaceuticals, food, cosmetics, plastics, paper, agro-chemistry and industrial applications.

作者简介

NISSIM GARTI 博士是拉特纳化学荣誉教授、耶路撒冷希伯来大学管理委员会成员、化学系配方中心负责人，也是多家全球公司的顾问。他创立了 Adumim Chemicals 的营养保健系统 (Nutralease) 和溶致性输送系统 (DLS)。

PONISSERIL SOMASUNDARAN 是哥伦比亚大学新型表面活性剂高级研究工业/大学合作研究中心主任。他的研究涉及矿物、材料和微生物的表面和胶体化学、表面分子相互作用以及环境工程。

RAFFAELE MEZZENGA 是苏黎世联邦理工学院的全职教授。他的研究重点是液晶聚合物、超分子聚合物、溶致液晶以及生物和食品胶体系统中的自组装过程。他曾获得软凝聚态领域的多项国际奖项，包括美国物理学会的约翰·H·狄龙奖章。

NISSIM GARTI, PhD, is the Ratner Honor Chair of Chemistry, member of the management committee of The Hebrew University of Jerusalem and the head of the Formulation Center of the Department of Chemistry, and advisor to several global companies. He established Adumim Chemicals' Nutraceutical Systems (Nutralease) and Delivery Lyotropic Systems (DLS).

PONISSERIL SOMASUNDARAN, is the Director of the Industry/University Cooperative Research Center for Advanced Studies in Novel Surfactants at Columbia University. His research examines surface and colloid chemistry of minerals, materials and microbes, molecular interactions at surfaces, and environmental engineering.

RAFFAELE MEZZENGA is Full Professor at ETH Zürich. His research focuses on self-assembly processes in liquid crystalline polymers, supramolecular polymers, lyotropic liquid crystals, and biological and food colloidal systems. He is a recipient of several international awards in the field of soft condensed matter, including the John H. Dillon Medal of the American Physical Society.

部分目录，仅供参考

Preface vii

Contributors xi

1. Physics of Self-Assembly of Lyotropic Liquid Crystals 1

Raffaele Mezzenga

2. Rheological Theory and Simulation of Surfactant Nematic Liquid Crystals 21

Alejandro D. Rey and E. E. Herrera-Valencia

3. Dividing Planes of Hexagonal HII Mesophase 79

Vesselin Kolev, Abraham Aserin, and Nissim Garti

4. Nanocharacterization of Lyotropic Liquid Crystalline Systems 97

Patrick G. Hartley and Hsin-Hui Shen

5. Self-Assembly in Lipidic Particles 129

Anan Yaghmur and Otto Glatter

6. Hierarchically Organized Systems Based on Liquid Crystalline Phases 157

Chandrashekhar V. Kulkarni and Otto Glatter

7. Synthesis and Alignment of Nanostructured Materials Using Liquid Crystals 193

Idit Amar-Yuli, Abraham Aserin, and Nissim Garti

8. Recent Developments in Lyotropic Liquid Crystals as Drug Delivery Vehicles 219

Dima Libster, Abraham Aserin, and Nissim Garti

9. Stimuli-Responsive Lipid-Based Self-Assembled Systems 257

Ben J. Boyd and Wye-Khay Fong

10. Nonlamellar Lipid Liquid Crystalline Structures at Interfaces 289

Debby P. Chang and Tommy Nylander

11. Multicompartment Lipid Nanocarriers for Targeting of Cells Expressing Brain Receptors 319

Claire Géral, Angelina Angelova, Borislav Angelov, Valérie Nicolas, and Sylviane Lesieur

Index 357